I recommend using Compressed Textures, it is our way moving forward with V-Ray GPU.
On one side, it preserves fine details in your textures and it works nicely with GPU LC. We will remove Mip mapped textures at one point
About performance with Compressed Textures, it should be close if you have one or 2 GPUs. It will be slower if you have multiple high-end GPUs, this we plan to improve in future