I think Vray has this option to render where the mouse pointer is.
Now that I have a 32 inch monitor I’m using the in-viewport IR. It’s great.
It’d be nice to have the option to have a check box that, when checked, it renders just a certain radius under the mouse pointer.
You can also zoom in while using IR, and only the visible area will be rendered, so sampling will be focused on that specific area.
The “sample brush” was requested few times, but I don’t think it’s coming any time soon (it would be probably too much work, and it’s not really requested often).
Yes, IR in viewport is quite limited in that regard. On the other hand, IR is meant to be interactive, you supposed to interact with objects in the viewport and/or adjust materials, it would be difficult to do that, if your mouse would hover over IR window, telling renderer where it needs to focus the samples :]