If medium-animation presets are giving you a consistant flicker free GI solution.. then that’s great. I find that I usually have to bump up to High-animation presest. Although admitedly I haven’t had a chance to fully use the animation-prepass mode. I’ve yet to see if by blending multiple irradiance maps together weither or not that allows you to use lower settings and still get a flicker free GI.
But if render time is going to be a problem.. I would suggest pre-calculating the irradiance maps. That way you may only need to render them out ever 10, 20 or even 30th frame or more, depending upon the movement of your camera.
Also.. I pretty much use light cache for secondary bounces.. it’s so much faster and wouldn’t use brute force unless I was having some kind of problem. Even then, I would probably try detail enancement before I would go to all brute force.
I output to RLAs and import into AE.
I’m sure that’s just some setting somewhere… sounds like maybe it’s getting double gammed?
Look on CG Architect at some of the Chicken Littles of the ArchViz industry and it is not hard to see why some of the secrets of really outstanding results are kept close to the vest.
Well.. I know you said that this is just a test in a “sand box”. And there’s lots of little details and such that you could add to the building, but in my opinion in most architectural exterior visualizations.. the best “secret” is outstanding landscaping. I mean sure.. there are buildings that speak for themselves and it would simply be hard NOT to create a great rendering of them… but most “ordinary” buildings, what I notice between an “ok” or even “good” rendering and an “outstanding” rendering… mostly comes from the attention to detail in the landscaping and the surrounding environment. Realistic grass, trees, bushes, flowers, mulch, rocks, shrubs, maybe some ivy growing up the side of the building, etc. Not only that they look realistic, but are landscaped in a way that would be realistic. Basically all the stuff that I never have time to put that much detail into
but I know it’s lacking.
Then not only the landscaping.. other enviromental details… like having people that are appropriate to the scene and doing things that help tell the story or set the mood of what you are trying to show. I know I have used endlessly (and continue to do so) RPC people in my scenes. This is simply do to budget and timelines.. not that I want to use them. Although RPCs are ok and a down and dirty way to get people into not only a scene but an animation, 9 out of 10 times the people are not exactly appropriate to what the scene is and the mood you might be trying to get accross. I just don’t have the time or budgets to green screen actors into my animations.
Being on a college campus.. you would most likely want college students (duh?), maybe a professor or two. And you would want them to be doing what college students do… walking to class, sitting under a tree in the grass reading a book, small groups of them here and there hanging out and talking, maybe someone running to catch up with someone else, maybe some students out on the lawn tossing a ball around or whatever. Obvisously also dressed in whatever timeframe (1900s?, 1920s?, etc) you are showing. But also appropriate to what mood are you trying to portray. The first nice day of spring (which is what I described above)? But could be somethign else. The excitment of the week before graduation? Homecomming week? A bleak cold winter day where everyone is just rushing from one building to another? A sad day in history of the start of world war II where everyone is a little worried and anxious?
Obviously if the attention to detail of the landscaping is no small task, having appropriate people (particularly in an animation) is a ginormous task.. especially when most of us are a sort of “jack of all trades” and have to produce animations from the start to finish with little or no help from others. Maybe you have a team of 2 or 3, but it’s not like most of us have a team of 20 or 30 people or more that each specialize in different areas like modeling, lighting, animating, compositing, video editing, F/x and so on. 
I know this is getting off the original topic of what setting to use for an animation.. but on the topic of what “secrets” there are to exterior visualizations.. I think that unless you have a really fantasical building to work with.. that the attention to detail of the environment around the building is the biggest “secret”.
The landscaping can make a good rendering a great one, and the appropriate people set in the stage and doing appropriate things for the mood you are trying to create can take it from a great rendering to an emotionally engaging one.
Sigh… now only if we had clients that would pay for these things.. 