Vrayphysicalcamera didn't update after changinfg value (f-Number / Shutter speed/ Iso...)

[fraggle]

Hello, I can't get the exposition done as the vrayphysicalcamera is not responding.
None of the value work, I have to close and open the scene again to get the change visible, but only one chance. After I need to close again.

Auto exposure is off, but the only way to get the change is by using the auto exposure, witch change the iso. But if I change the iso by myself nothing happens, after unchecking auto exposure.
What should I do?