I swear that I am cursed and keep finding weird bugs.
Recently I have been working on something where I keep checking the light levels in Viewport IPR and with the Safe Frames Off, it renders perfectly fine. Turn the safe frames on however, and everything shunts over to the left.
Did you install update 2 for 3ds Max 2021? Autodesk changed the way safe frames work in the viewport. If you get the latest V-Ray 5 stable build from our website nightlies.chaosgroup.com, this should be fixed.