Render Region other than a Sqaure

+1 for a lasso selection tool!

I’ve had this happen so many times where I need to re-render an organic shape and it would be so much faster if I could have selected the exact area.

I have done it before with the “matte box” approach i mentioned earlier, basically with a UV mapped rectangle, with a spline inside, animated vertices. Linked to the camera.
You still have to comp it afterwards, but it saved me a ton of render time.